Structure-Activity of Sulfones and Sulfonamides on Dihydropteroate Synthetase from Neisseria meningitidis
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چکیده
منابع مشابه
Structure-activity of sulfones and sulfonamides on dihydropteroate synthetase from Neisseria meingitidis.
The molecular interaction of various sulfones and sulfonamides with partially purified dihydropteroate synthetase from Neisseria meningitidis M-166 has been examined. The mode of action of the sulfones was similar to that of the sulfonamides. Both groups of drugs were competitive inhibitors of dihydropteroate synthetase with respect to p-aminobenzoate in a partially purified enzyme preparation....
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 1975
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.7.6.758